The witch trials: the type of girl he uses would almost certainly be suspected
The plague: I'm not keen on using this, as it isn't specific to women
The French Revolution:Female members of the aristocracy would be better fed than peasants and therefore be healthier
The wives of Henry VIII
Any other examples where a woman/women have been targeted and killed in any period in history, preferably in Europe, would be really helpful.
Time isn't an issue as he is pretty much immortal.